Circulating Tumor DNA-Guided Adjuvant Therapy: Recent Advances and Clinical Implications (2021–2025)
Highlights
- Circulating tumor DNA (ctDNA) is increasingly validated as a biomarker to guide adjuvant therapy decisions across multiple solid tumors.
- Recent prospective studies and trials demonstrate that ctDNA-guided strategies can personalize adjuvant treatment, potentially reducing overtreatment and improving outcomes.
- Technological advances in ctDNA detection and quantification provide enhanced sensitivity for minimal residual disease detection, enabling earlier intervention.
- Challenges remain in standardization, optimal timing, and integration into clinical guidelines, warranting further large-scale randomized studies.
Background
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.