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Anatomic First or Invasive Angiography First? DISCHARGE Shows No QOL Advantage for CT over ICA in Stable Chest Pain

MedXY Editorial Team•Dec 3, 2025•Cardiology
invasive coronary angiographyquality of life

Highlights

– In the DISCHARGE prespecified secondary analysis, an initial CT-first strategy yielded no clinically meaningful advantage over an ICA-first strategy in patient-reported quality of life (QOL) or angina at a median 3.5 years of follow-up.

– Both groups experienced small but statistically significant improvements in several QOL domains; clinically important differences were generally absent.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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