AI Model Shows Moderate Accuracy for Predicting Complete Response After Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer
Highlights
An ensemble of fine-tuned tabular foundation models predicted pathological complete response after total neoadjuvant therapy and total mesorectal excision with moderate discrimination in locally advanced rectal cancer.
In the surgical development cohort, model performance was AUROC 0.71, AUPRC 0.44, and Brier score 0.17, suggesting reasonable ranking ability and acceptable calibration.
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.