Weight Reduction Before Conception: Enhancing Fertility and Reducing Pregnancy Complications in Overweight and Obese Women
Highlights
- Preconception weight loss of 10%-25% modestly increases pregnancy rates (~5% over 3 years) among overweight and obese women.
- Weight loss prior to conception is associated with significant reductions in gestational diabetes, pregnancy-induced hypertension, and emergency cesarean delivery.
- Lifestyle interventions, including diet and exercise, and in select cases weight-loss medications, are important tools to improve reproductive outcomes; however, timing and cessation before conception should be carefully managed.
- Bariatric surgery shows promise in improving spontaneous ovulation and fertility in obesity-related anovulatory infertility, such as polycystic ovary syndrome.
Background
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.