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Understanding Placenta Accreta Spectrum: Gaps in Global Guidelines and the Path Forward

MedXY Editorial Team•Sep 30, 2025•news
clinical guidelinesmaternal healthPlacenta accreta spectrum

Placenta accreta spectrum (PAS) disorders represent a critical challenge in maternal health, characterized by abnormal adherence of the placenta to the uterine wall, often resulting in severe complications during delivery. As cesarean deliveries (CD) continue to rise globally, so does the incidence of PAS, necessitating robust clinical practice guidelines (CPGs). A recent study published in JAMA Network Open underscored significant gaps in these guidelines, particularly between high-income countries and low- and middle-income countries (LMICs).

Scientific and Clinical Evidence: What the Data Tell Us

The systematic review analyzed CPGs from January 2014 to January 2024, focusing on PAS and related CD recommendations. Researchers identified 18 relevant articles: 14 primarily dealing with PAS and four addressing CD or postpartum hemorrhage management. The findings revealed discrepancies across guidelines, including risk factor identification, screening protocols, and management strategies.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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