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Tirzepatide Shows Promising Efficacy and Safety in Managing Youth-Onset Type 2 Diabetes: Insights from the SURPASS-PEDS Trial

MedXY Editorial Team•Oct 10, 2025•Diabetes & Endocrinology
GLP-1 receptor agonistpediatric endocrinologytirzepatidetype 2 diabetes

Highlight

Tirzepatide, a dual GIP and GLP-1 receptor agonist, significantly reduced HbA1c and BMI in youth with type 2 diabetes compared to placebo over 30 weeks, with sustained benefits up to 52 weeks. The safety profile was consistent with previous adult data, primarily mild to moderate gastrointestinal adverse events.

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