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One-Year Tumor Volume Regression as a Predictor of Survival in I-125 Plaque Brachytherapy for Posterior Uveal Melanoma

By MedXY|Aug 4, 2026

Tumor volume regression at one year post-I-125 plaque brachytherapy significantly predicts overall survival in posterior uveal melanoma, with intermediate regression showing the best outcomes.

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MBD4 Germline Variants Mark a Strong Predisposition to Uveal Melanoma, Supporting Broad Genetic Screening

By MedXY|May 4, 2026

A large French case series found pathogenic or likely pathogenic germline MBD4 variants in 23 of 896 patients with uveal melanoma, corresponding to a 31-fold relative risk versus the general population.