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Cardiology

Gout as a Modifiable Risk Factor for Ischemic Stroke in Atrial Fibrillation: Insights from the FinACAF Study

This nationwide Finnish cohort study reveals that gout increases ischemic stroke risk in atrial fibrillation patients, with urate-lowering therapy linked to reduced stroke incidence, underscoring gout’s potential role in stroke risk s

Aug 19, 2026
Cardiology

Redefining Gout Management: Cardiovascular Risk Reduction via Treat-to-Target Urate-Lowering Therapy

Achieving serum urate targets <6 mg/dL (or <5 mg/dL) through Treat-to-Target (T2T) protocols significantly reduces major adverse cardiovascular events in gout patients, particularly those at high baseline risk.

Mar 25, 2026
Clinical Updates

Long-Term Impact of Treat-to-Target Urate-Lowering Therapy on Ultrasound-Detected Crystal Depositions and Clinical Outcomes: Insights from the 5-Year NOR-Gout Study

The 5-year NOR-Gout study demonstrates that sustained low serum urate via treat-to-target therapy leads to dissolution of crystal deposits, reduced flares, and increased remission rates, highlighting the clinical value of long-term urate co

Dec 4, 2025
news

Sustained Treat‑to‑Target Urate‑Lowering Therapy Clears Crystal Deposits and Cuts Flares: 5‑Year NOR‑Gout Follow‑Up

Five‑year follow‑up of the NOR‑Gout treat‑to‑target urate‑lowering therapy program shows durable serum urate control, marked reduction and frequent dissolution of ultrasound‑detected MSU deposits, and a low residual flare rate linked to hig

Dec 3, 2025
Clinical Updates

Epaminurad: A Promising hURAT1 Inhibitor for Effective and Safe Gout Management – Insights from a Phase 2b Dose-Finding Trial

Epaminurad significantly lowers serum urate levels in gout patients with excellent safety, offering a promising alternative to existing therapies. This randomized controlled trial identifies optimal dosing and confirms tolerability over 12

Aug 26, 2025Sign in to read

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