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The TC-MAX is the first validated, disease-specific instrument measuring thyroid cancer-related anxiety, showing strong reliability and validity to inform treatment decisions and improve patient-centered care.
This retrospective study assesses the efficacy and safety of pemetrexed, alone or combined with carboplatin, as salvage therapy for advanced thyroid cancer, showing promising response rates comparable to current second-line treatments.
Erythrocytosis is an underreported hematologic side effect of targeted therapies in advanced thyroid cancers, notably RET inhibitors, occurring early and recurrently without impacting survival outcomes but correlating with disease control r
A real-world study validates the 2025 ATA thyroid cancer risk guidelines, showing significant patient reclassification and identifying a new ‘low-intermediate-risk’ group needing tailored management approaches.
A prospective study identifies exhaustion, head and neck discomfort, and body image concerns as independent predictors of poor emotional functioning in differentiated thyroid carcinoma patients. These findings highlight actionable targets f
A nationwide cohort study highlights that thyroid cancer patients with permanent hypoparathyroidism face significantly elevated risks of kidney stones, renal failure, and major cardiovascular events, necessitating comprehensive long-term fo
A large-scale Korean cohort study reveals thyroid cancer survivors face a significantly higher risk of depression in the first five years post-diagnosis, independent of treatment modality or hormone dosage.
A prospective cohort study reveals that patients with low-risk papillary thyroid cancer experience similar quality of life outcomes at three years whether they choose active surveillance or immediate surgery, though those who crossover to s
This review details the development and psychometric validation of the TCQOLI, a novel thyroid-cancer-specific utility measure designed to provide precise preference-based health state valuations for clinical research and policy-making.
A new study suggests that isolated RAS mutations in Bethesda III and IV thyroid nodules do not always require surgery. With a 34% malignancy rate and low growth incidence, active surveillance emerges as a viable, safe alternative for approp
Thyroid cancer treatments in young women are linked to increased infertility diagnosis and early menopause but show no significant association with premature ovarian insufficiency or reduced childbirth rates.
A 185-country study shows large, sustained increases in thyroid cancer incidence among adolescents and young adults (15–39 years) since the 2000s while mortality remains low and stable — a pattern most consistent with widespread overdiagnos
A US cohort study (Sister Study) found that recent use of hair straighteners/chemical relaxers was associated with higher incidence of thyroid cancer, pancreatic cancer, and a possible increase in non‑Hodgkin lymphoma; associations were imp
This study reveals that increased serum free thyroxine and insulin resistance-associated factors are linked to higher malignancy risk in thyroid nodules, suggesting a complex interplay between metabolic and hormonal factors in thyroid cance