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The PROFID study reveals a declining mortality benefit from primary prevention implantable cardioverter-defibrillators in post-myocardial infarction patients with reduced ejection fraction over recent decades, highlighting changing clinical
An international multicenter study shows ICDs effectively prevent sudden death in high-risk hypertrophic cardiomyopathy patients, demonstrating low mortality rates and significant lifesaving interventions over long-term follow-up.
This study reveals that two-thirds of community sudden cardiac deaths occur in individuals without diagnosed cardiac disease, with half harboring occult myocardial infarction or dilated cardiomyopathy, underscoring the need for improved det
A 5-generation French Canadian family with history of sudden cardiac death was diagnosed with calcium release deficiency syndrome using a novel burst pacing provocation test, illustrating its clinical utility and highlighting the importance
A Danish nationwide study found substantially higher sudden cardiac death rates in both type 1 and type 2 diabetes, especially at younger ages, with meaningful loss of life expectancy attributable to sudden cardiac death.
A nationwide Danish study found that type 1 and type 2 diabetes substantially increase sudden cardiac death risk, especially in younger adults, and contribute meaningfully to shortened life expectancy.
A multiregistry analysis reveals that massive LVH in pediatric HCM is linked to early diagnosis, sarcomeric mutations, and heightened risks of arrhythmias, heart failure, and mortality. Nearly 25% of patients show significant LVH regression
The extended 13.2-year follow-up of the DANISH trial demonstrates that while primary prevention ICDs do not reduce all-cause mortality in nonischemic HFrEF overall, they significantly lower sudden cardiovascular death risk, particularly in
The nationwide HONEST study provides critical five-year data on S-ICD performance, highlighting a 13.8% inappropriate shock rate, the protective effect of SMART Pass filtering, and unexpected challenges with battery longevity in a large, un
A large-scale registry study confirms that procainamide infusion is exceptionally safe for Brugada syndrome diagnosis, with high sensitivity and specificity. Crucially, asymptomatic patients with a procainamide-induced type 1 pattern demons
The nationwide SCD‑PROTECT study (n=19,598) found substantial early risk of sustained VT/VF in newly diagnosed ischaemic and non‑ischaemic cardiomyopathy; wearable cardioverter‑defibrillators (WCDs) delivered life‑saving therapy with low in
A mild-to-significant decline in left ventricular ejection fraction (LVEF) in heart failure with preserved ejection fraction (HFpEF) signals higher risks of lethal arrhythmias, sudden cardiac death, and mortality, underscoring the need for
Understanding sudden cardiac death, its warning signs, primary risk factors, and preventive measures to safeguard heart health.
