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Cardiology

Integrating Metabolomics and Polygenics with SCORE2: A New Frontier in Cardiovascular Risk Stratification

A large-scale UK Biobank study demonstrates that combining NMR metabolomics, polygenic risk scores, and clinical biomarkers with SCORE2 significantly enhances cardiovascular risk prediction, potentially doubling the number of prevented even

Jan 5, 2026
Clinical Updates

Precision in Prevention: The Role of Prediction-Augmented Shared Decision-Making in Enhancing Lung Cancer Screening Uptake

This review evaluates the impact of integrating risk-prediction models into shared decision-making for lung cancer screening, focusing on clinical implementation strategies that prioritize high-benefit populations.

Dec 28, 2025
Superintelligence

Artificial Intelligence-Enabled Prediction of Heart Failure Risk From Single-Lead Electrocardiograms: A Multinational Cohort Review

This review evaluates AI algorithms predicting heart failure risk from noisy single-lead ECGs, synthesizing evidence from large multinational cohorts, highlighting improved risk stratification with AI-ECG models beyond traditional clinical

Dec 5, 2025
Cardiology

Predicting Heart Failure Risk in Women Treated for Breast Cancer: A New Clinical Tool

A novel risk prediction model for 10-year heart failure or cardiomyopathy offers tailored cardiac management strategies for women undergoing breast cancer therapy.

Oct 24, 2025
Cardiology

Triglyceride Glucose-Waist Height Ratio Index as a Predictor of Cardiometabolic Multimorbidity in Chinese Middle-Aged and Older Adults: Insights from a National Prospective Cohort Study

This study demonstrates that the triglyceride glucose-waist height ratio (TyG-WHtR) index independently predicts cardiometabolic multimorbidity risk in Chinese adults aged ≥45, showing a linear dose-response relationship and improved predic

Oct 19, 2025Sign in to read
Cardiology

Insulin Resistance Indices as Predictors of Cardio-Renal-Metabolic Multimorbidity: Insights from the UK Biobank

This study demonstrates that insulin resistance indices, particularly TyG-WC, TyG-WHtR, and METS-IR, robustly predict the risk and progression of cardio-renal-metabolic multimorbidity, with inflammation and kidney function mediating these a

Oct 19, 2025
Superintelligence

Harnessing Machine Learning to Predict High-Risk Coronary Artery Disease: Insights from the SCOT-HEART Trial

Machine learning models trained on clinical data improve prediction of coronary artery disease on CT scans compared to traditional risk scores, potentially guiding better resource utilization in cardiovascular care.

Sep 14, 2025
Superintelligence

Beyond Binary: Unveiling the Broad Cardiovascular Insights of AI-enhanced Electrocardiography

AI-enhanced ECG models, initially designed for specific cardiac diagnoses, reveal broader cardiovascular risk detection and prediction capabilities, challenging their use as condition-specific tools and supporting their role as comprehensiv

Sep 6, 2025
Cardiology

Enhancing Cardiovascular Risk Prediction and Outcomes with Coronary CT Angiography: Insights from the PROMISE and SCOT-HEART Trials

Coronary CTA, guided by clinical risk models and advanced radiomic plaque analysis, improves prediction and prevention of myocardial infarction in patients with new-onset chest pain, particularly in those with low clinical likelihood of cor

Aug 16, 2025
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