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Spectacle Lenses With Highly Aspherical Lenslets for Myopia Control: A Comprehensive Review of Recent Clinical Trials and Emerging Evidence

This review synthesizes recent randomized clinical trials and real-world studies confirming the safety and efficacy of highly aspherical lenslets (HAL) spectacle lenses in slowing myopia progression among children, emphasizing comparative e

Aug 23, 2026

Clinical Updates

Tailored Weight Loss Interventions in Serious Mental Illness: A Comprehensive Review of Evidence and Clinical Implications

This review synthesizes evidence on tailored weight loss programs for adults with serious mental illness, highlighting recent advances, effectiveness, mechanistic insights, and future directions.

Dec 24, 2025

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Limited Direct Comparison of Me-Too Oncology Drugs with First-in-Class Agents: Clinical Implications and Regulatory Considerations

Analysis of FDA approvals from 2009–2020 reveals only 29% of next-in-class oncology drugs underwent head-to-head RCTs against originals, with just 22% showing survival benefits, highlighting a need for incentivized comparative trials.

Jul 31, 2025