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Long-Term Risk of Second Primary Malignancies in Pediatric and Young Adult Differentiated Thyroid Cancer Survivors: A Four-Decade Real-World Study
newsdifferentiated thyroid cancerRadioactive Iodine

Long-Term Risk of Second Primary Malignancies in Pediatric and Young Adult Differentiated Thyroid Cancer Survivors: A Four-Decade Real-World Study

By MedXY|Aug 17, 2026

Pediatric and young adult survivors of differentiated thyroid cancer face a significant long-term risk of second primary malignancies, especially with radioactive iodine treatment, highlighting the need for extended surveillance and tailore

Detectable Antithyroglobulin Antibodies Above the Assay LOQ Signal Higher Recurrence Risk in Papillary Thyroid Carcinoma Despite Undetectable Thyroglobulin
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Diabetes & Endocrinology
antithyroglobulin antibodies
Papillary Thyroid Carcinoma

Detectable Antithyroglobulin Antibodies Above the Assay LOQ Signal Higher Recurrence Risk in Papillary Thyroid Carcinoma Despite Undetectable Thyroglobulin

By MedXY|Jun 3, 2026

In papillary thyroid carcinoma treated with thyroidectomy and RAI, TgAb levels above the assay’s limit of quantification identified patients with higher long-term recurrence risk despite undetectable serum thyroglobulin.

ATA Guideline Updates Reduced Thyroid Cancer Overtreatment in a 31,861-Patient South Korean Cohort
General SurgeryATA guidelinesPapillary Thyroid Carcinoma

ATA Guideline Updates Reduced Thyroid Cancer Overtreatment in a 31,861-Patient South Korean Cohort

By MedXY|Apr 30, 2026

A large South Korean cohort found ATA-guideline de-escalation reduced total thyroidectomy, RAI use, and permanent hypocalcemia in papillary thyroid carcinoma, without significant loss of 5-year disease-free survival.

De-escalating Management of N1b Papillary Thyroid Carcinoma: Are Total Thyroidectomy and RAI Mandatory for All?
Diabetes & EndocrinologyLateral Neck MetastasisPapillary Thyroid Carcinoma

De-escalating Management of N1b Papillary Thyroid Carcinoma: Are Total Thyroidectomy and RAI Mandatory for All?

By MedXY|Dec 24, 2025

A multicenter study challenges the mandatory use of total thyroidectomy and radioactive iodine in all patients with lateral neck metastasis (cN1b) papillary thyroid carcinoma, suggesting that lobectomy may offer comparable oncologic outcome

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