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A statewide Australian cohort study reveals lithium exposure during pregnancy doubles risk of spontaneous preterm birth and raises risks of cardiac malformations and large-for-gestational-age infants, informing clinical decision-making.
Pregnant and postpartum individuals continue to face higher risks of severe COVID-19 outcomes, including hospitalization and pneumonia, even after the pandemic emergency has ended, emphasizing the need for ongoing vigilance and tailored cli
This article reviews updated clinical understanding of Ebola virus disease in pregnancy amid the Democratic Republic of Congo outbreak, highlighting maternal outcomes, risks of vertical transmission, treatment challenges, and the critical n
A large-scale VSD study found that prenatal vaccination with bivalent prefusion F RSV vaccine is generally safe, showing no increased risk for preterm birth, stillbirth, or small-for-gestational-age births but a slight increase in hypertens
Hantavirus infection in pregnancy is rare but potentially fatal. Obstetricians should suspect it after rodent or travel exposure, recognize rapid respiratory decline, and prioritize supportive critical care because no proven antiviral thera
The iSCAD Registry study highlights distinctive reproductive and psychosocial features among women with pregnancy-associated SCAD, underscoring the need for individualized counseling, heightened diagnostic suspicion, and multidisciplinary f
A nationwide Dutch study suggests pregnancy in women with peripheral vascular malformations is frequently complicated by symptom progression and postpartum hemorrhage, with venous thromboembolism concentrated in extensive lower-extremity ma
An Australian cohort study found that prenatal exposure to valproate, levetiracetam, topiramate, and carbamazepine was associated with poorer cognitive outcomes in children, while lamotrigine exposure was not.
Thyroid abnormalities found during pregnancy, especially when subclinical hypothyroidism and TPO antibodies coexist, can signal a much higher long-term risk of overt hypothyroidism, supporting ongoing thyroid follow-up after delivery.
In a retrospective cohort of pregnancies complicated by type 2 diabetes, gestational weight gain under 5 kg was associated with lower odds of several adverse perinatal outcomes without a statistically significant rise in preterm birth or sm
A prespecified CIRCUIT analysis found that Control-IQ closed-loop insulin delivery improved intrapartum time in range and reduced early postpartum hypoglycemia versus standard care in women with type 1 diabetes, without new safety concerns.
Higher proteinuria in preeclampsia was linked to greater long-term risk of maternal hypertension and chronic kidney disease, with overall increased risk of cardiovascular disease as well.
A clinical trial found that weekly extended-release buprenorphine significantly improves illicit opioid abstinence during pregnancy compared to sublingual forms, with fewer serious adverse events, offering a safer treatment option for opioi
In this post hoc analysis of a large randomized pregnancy trial, aspirin’s effects on preterm birth and perinatal mortality were not meaningfully modified by gestational age at initiation or measured adherence.
In a pooled U.S. pregnancy cohort, maternal PFAS concentrations were not associated with a higher prevalence of gestational diabetes, and fasting glucose findings were largely null.
The ESC EORP ROPAC III registry highlights a stark contrast in pregnancy outcomes between mechanical and biological heart valves, revealing that only 54% of women with mechanical valves achieve an uncomplicated live birth, largely due to an
This review analyzes the lifestyle patterns of pregnant women with type 1 diabetes, synthesizing findings from the ENDIA study with recent evidence on nutritional adequacy, islet autoimmunity, and the molecular mechanisms of metabolic compe
Research indicates that achieving stable and optimal blood sugar levels immediately after a gestational diabetes diagnosis can reduce a child’s risk of obesity to levels comparable to those born to mothers without the condition.
This review synthesizes findings on how pregnancy biomarkers, particularly sFlt-1 and hs-cTnI, serve as early indicators of long-term maternal cardiovascular risk, offering a unique window for sex-specific prevention.
This clinical review synthesizes findings from the PRETHYR study on antithyroid drug use in pregnant women, highlighting treatment transitions, biochemical predictors, and the impact of specialist-led management in Denmark.
