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This exploratory trial compares cobratide injection and pregabalin for moderate-to-severe acute herpes zoster neuralgia, showing similar pain relief with better tolerability for cobratide and a potential reduction in postherpetic neuralgia
Pregabalin, a neuromodulator, significantly improves symptoms in the majority of patients with chronic neurogenic cough, offering a well-tolerated treatment option irrespective of gender or gastrointestinal comorbidities.
A recent decision analytical model identifies duloxetine 120 mg as the most cost-effective treatment for moderate-to-severe fibromyalgia, providing superior clinical outcomes at a marginal cost increase compared to amitriptyline, particular
In a mouse spared nerve injury model, pregabalin—but not morphine—restored REM sleep, normalized locomotor and temperature circadian rhythms, and reversed spinal circadian gene changes. Findings suggest analgesic choice can differentially a
New data show an increased risk of heart failure among elderly Medicare patients initiating pregabalin versus gabapentin for chronic noncancer pain, particularly in those with cardiovascular disease history.
