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Transformative Survival Gains in Cystic Fibrosis: A Population-Level Evaluation of CFTR Modulator Therapy Effectiveness

A large-scale retrospective study using US CFF Registry data reveals that CFTR modulator therapy reduces the hazard of death by 66% over an eight-year period, marking a significant milestone in cystic fibrosis clinical outcomes and life exp

May 14, 2026
Cardiology

The Changing Landscape of Mortality in Diabetes: A Shift from Cardiovascular Dominance to Cancer and Dementia

This review analyzes multinational data showing a significant decline in cardiovascular mortality among diabetes patients, alongside a concerning rise in dementia-related deaths and the emergence of cancer as a leading cause of mortality in

Mar 14, 2026
Cardiology

Cardiovascular Risk Scores Overestimate Mortality in Mexican Adults: The Urgent Need for Population-Specific Recalibration

A prospective study of over 112,000 adults in Mexico City reveals that standard CVD risk scores consistently overestimate 10-year fatal risk. Recalibration of the Globorisk-fatal model significantly improves predictive accuracy, highlightin

Mar 4, 2026
Cardiology

Heart Failure Mortality: The Resilient Challenge in an Era of Declining Cardiovascular Deaths

This multi-national analysis of 2.92 million deaths highlights a concerning trend: while coronary and stroke mortality have plummeted, heart failure mortality remains stagnant or rising, with people with diabetes bearing a disproportionate

Dec 20, 2025
Cardiology

Unlocking Echocardiograms to Treat Undiagnosed Hypertension — The NOTIFY‑LVH Randomized Trial

A centralized notification and support pathway using prior echocardiographic LVH increased antihypertensive initiation and new hypertension diagnoses versus usual care in a pragmatic randomized trial.

Dec 3, 2025Sign in to read
Clinical Updates

Optimizing Colorectal Cancer Screening Outreach for Adults Aged 45-49: Insights From a Large-Scale Randomized Trial

A large UCLA Health randomized clinical trial found that usual care via mailed FIT outreach outperformed active choice strategies in colorectal cancer screening uptake among adults aged 45 to 49 years, highlighting the challenges in engagin

Sep 13, 2025Sign in to read

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  1. 01Intimate Health

    Five Benefits for Women Continuing Sexual Activity After Menopause

  2. 02Intimate Health

    Why Some Women Have a Strong Sex Drive—And Why Men Shouldn't Worry About It

  3. 03Nursing & care

    How often should a couple have sex?

  4. 04Cardiology

    Precision Medicine for Long QT Syndrome Type 2: Lumacaftor Corrects Trafficking Defects and Shortens QT Interval

  5. 05General Surgery

    Optimizing Postoperative Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Comparing the 5x-Multiplier and 3-Tier Models

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