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Gestational Changes in Antiseizure Medication Concentrations and the Impact of Polytherapy: Insights from a Prospective Multicenter Cohort Study in China
Clinical Updatespolytherapylamotrigine

Gestational Changes in Antiseizure Medication Concentrations and the Impact of Polytherapy: Insights from a Prospective Multicenter Cohort Study in China

By MedXY|Sep 8, 2026

Pregnancy significantly reduces antiseizure medication concentrations, with lamotrigine showing the greatest decline. Polytherapy and body weight modulate these changes, underscoring the importance of individualized therapeutic drug monitor

Antiseizure Medication Use During Pregnancy: Implications for Fetal Growth from the EURAP Registry
NeurologyTăng trưởng thai nhi
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Pregnancy

Antiseizure Medication Use During Pregnancy: Implications for Fetal Growth from the EURAP Registry

By MedXY|Sep 5, 2026

A comprehensive cohort study from the EURAP registry reveals that antiseizure medication, especially polytherapy and certain monotherapies, increases the risk of poor fetal growth, underscoring the need for optimized treatment strategies du

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