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Polymyalgia Rheumatica

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Rheumatology

When and How to Image Polymyalgia Rheumatica: International Recommendations for a Targeted, Evidence-Based Approach

New international recommendations position imaging as a context-driven adjunct in polymyalgia rheumatica (PMR): not routine for clear cases, most helpful in intermediate or atypical presentations, and not recommended for routine monitoring.

Nov 4, 2026
Diabetes & Endocrinology

Can an 11β‑HSD1 Inhibitor Improve Prednisolone’s Benefit–Risk Ratio in Polymyalgia Rheumatica? Early Human Trial Suggests Feasibility

A single‑blind sequential cohort trial found that clofutriben, a selective 11β‑HSD1 inhibitor, reduced biomarkers of glucocorticoid toxicity while partially attenuating prednisolone efficacy at low doses; efficacy was restored at higher pre

Dec 5, 2025Sign in to read
Clinical Updates

Sarilumab in Relapsing Polymyalgia Rheumatica: Clinical Efficacy and Patient-Reported Outcomes from Recent Phase 3 Trials

Sarilumab demonstrates significant improvement in disease control and quality of life for patients with relapsing polymyalgia rheumatica, enabling glucocorticoid sparing and sustained remission.

Aug 2, 2025
Clinical Updates

Polymyalgia Rheumatica Not Associated with Increased Mortality: Insights from a 38-Year Norwegian Cohort Study

A 38-year prospective study in Southern Norway demonstrates that isolated polymyalgia rheumatica (PMR) does not increase all-cause mortality compared to matched population controls, with men showing even lower mortality risk.

Jul 31, 2025

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