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pharmacovigilance

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OB/GYN & Women's Health

Evaluating Meningioma Risk in Users of Estro-Progestin and Progestin-only Therapies: Insights from EudraVigilance Pharmacovigilance Data

A pharmacovigilance study using EudraVigilance data highlights potential safety signals linking desogestrel-only and drospirenone-only hormonal therapies with meningioma, underscoring the need for further longitudinal research and cautious

Oct 31, 2026
Dentistry

GLP-1 Receptor Agonists in Dentistry: Exploring Therapeutic Promise Amidst Clinical Uncertainties

GLP-1 receptor agonists exhibit promising osteoprotective and anti-inflammatory effects in preclinical dental studies but lack robust clinical data, underscoring urgent research needs on their oral health impact and safety profile.

Oct 18, 2026
Diabetes & Endocrinology

GLP-1 Receptor Agonists and the Risk of Ischemic Optic Neuropathy in Type 2 Diabetes: Evidence from a Target Trial Emulation

This study evaluates the association between GLP-1 receptor agonists and ischemic optic neuropathy risk compared to SGLT2 and DPP-4 inhibitors, revealing a small but statistically significant increased risk with GLP-1RAs, particularly among

Jul 17, 2026
Clinical Updates

Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy: Synthesizing Evidence from Target Trial Emulations and Global Pharmacovigilance

This review synthesizes recent evidence regarding the association between semaglutide initiation and nonarteritic anterior ischemic optic neuropathy (NAION), contrasting high-risk findings in real-world cohort studies with neutral findings

Apr 2, 2026
Cardiology

Challenging the Label: Large-Scale Meta-Analysis Refutes Most Statin-Attributed Adverse Effects

A comprehensive meta-analysis of double-blind RCTs by the CTT Collaboration reveals that the majority of adverse effects listed on statin labels, including cognitive and sleep issues, lack causal evidence, suggesting a need for urgent regul

Feb 16, 2026Sign in to read
Dermatology

Immune Checkpoint Inhibitors Amplify Risk and Delay Onset of SJS/TEN: Evidence for a Two‑Hit Mechanism

A large FAERS analysis links immune checkpoint inhibitors (ICIs) to markedly increased SJS/TEN risk, demonstrates additive synergy with high‑risk small molecules, and shows delayed latency particularly with anti–PD‑1 agents — supporting a t

Nov 12, 2025

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