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This multicentre Italian study comparing clarithromycin and azithromycin for hospitalized infants with pertussis shows clarithromycin is linked to better clinical outcomes, including lower severity and fewer ICU admissions.
A phase 4 trial in The Gambia reveals that maternal Tdap-IPV vaccination provides early mucosal IgG to infants, while the DTwP primary series induces significantly stronger mucosal antibody and T-cell responses than DTaP, despite maternal a
A phase 4 trial in The Gambia finds that maternal Tdap-IPV vaccination is safe and provides early infant protection, but modestly blunts immune responses to whole-cell pertussis vaccines without compromising overall immunogenicity.
