Tag
This multicenter study reveals that among HLHS subtypes, mitral stenosis and aortic atresia with ventriculocoronary connections have the poorest transplant-free survival, highlighting the prognostic importance of prenatal and postnatal VCC
Retrospective multi-center data demonstrate that sotatercept improves functional status, exercise capacity, and hemodynamics in children with pulmonary hypertension, with a manageable safety profile.
A large registry study found that genetic cardiomyopathy risk varies by sex, age, and gene. TTN truncating variants were more common and earlier in males, while DSP and non-TTN sarcomeric variants were more common in females.
A multiregistry analysis reveals that massive LVH in pediatric HCM is linked to early diagnosis, sarcomeric mutations, and heightened risks of arrhythmias, heart failure, and mortality. Nearly 25% of patients show significant LVH regression
Recent research highlights a standardized multidisciplinary protocol for managing unilateral vocal fold immobility in infants after cardiothoracic surgery, showing that injection laryngoplasty significantly improves oral feeding advancement
A 16-year follow-up of the SVR trial reveals that while shunt types show similar long-term outcomes overall, pre-existing tricuspid regurgitation significantly impacts survival with RVPAS, amid a staggering 87% rate of major morbidity.
The ORION-16 trial demonstrates that inclisiran, a twice-yearly siRNA therapy, significantly and safely reduces LDL cholesterol in adolescents with heterozygous familial hypercholesterolaemia, offering a promising solution for long-term adh
A multicenter trial confirms the Minima Stent’s efficacy in treating pulmonary artery stenosis and aortic coarctation in infants. With a 97.6% success rate and growth-accommodating design, it addresses a critical unmet need in pediatr
This multicenter study highlights the utility of 2D speckle tracking echocardiography for early detection and prognostication of left ventricular dysfunction in MIS-C, informing cardiovascular risk and management.
