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Prolonged intubation, rather than tracheostomy placement, is associated with poorer neurodevelopmental outcomes in infants with severe bronchopulmonary dysplasia, highlighting the need to reassess timing of airway interventions.
A multicountry follow-up study found no significant improvement in neurodevelopmental outcomes at two years in infants with birth asphyxia whose mothers received a single 2 g oral dose of azithromycin during labor versus placebo.
This study reveals that among term births, fetal size at birth more strongly predicts long-term neurodevelopmental outcomes than gestational age, with small-for-gestational-age infants demonstrating persistent academic challenges into adole
Elevated maternal third-trimester TRAb levels in Graves’ disease are linked to neonatal thyroid dysfunction and impaired neurodevelopment at 24 months, independent of neonatal thyroid status, highlighting the need for prenatal monitor
This study found no association between neonatal hypoglycemia in late preterm infants and adverse neurodevelopmental outcomes at age 6 years or older.
This cohort study assesses the influence of hysterosalpingography with iodinated contrast on neurodevelopmental outcomes in children, revealing lower IQ scores in those conceived shortly after the procedure, warranting further investigation
In very preterm infants, thicker retinal nerve fiber layer on OCT at 36 weeks’ postmenstrual age was associated with better motor and cognitive outcomes at 2 years, supporting retinal imaging as a potential early neurodevelopmental biomarke
A new prospective cohort study suggests that retinal nerve fiber layer thickness on neonatal OCT at 36 weeks’ PMA may help predict 2-year motor and cognitive outcomes in very preterm infants.
A nationwide cohort study of 466,462 infants reveals that maternal pregestational diabetes significantly increases the risk of delayed developmental milestones, with type 1 diabetes conferring the highest risk and female offspring showing p
This review analyzes the association between in utero prescription opioid exposure and third-grade academic outcomes, highlighting a distinct risk signal for tramadol compared to codeine and oxycodone **Outlining Key Sections** I’m no
A comprehensive study highlights that over half of publicly insured children develop neurodevelopmental disorders within five years of infant cardiac surgery. While service utilization is high, a critical gap persists between initial screen
A secondary analysis of a randomized clinical trial reveals that parent-led enhanced developmental intervention, beginning in the NICU and spanning two years, significantly improves executive function domains—including attention, inhibition
Recent large-scale cohort studies suggest that previously observed links between prenatal exposure to acid-suppressants or antipsychotics and neurodevelopmental disorders are largely due to familial confounding. Conversely, active maternal
This large-scale study of 35,751 children characterizes ARFI phenotypes, revealing a 6.3% clinical prevalence and significant genetic heritability. Findings link ARFI to the ADCY3 locus and long-term neurodevelopmental difficulties, emphasi
A Cochrane meta-analysis of six RCTs (3,451 infants) finds restrictive hemoglobin thresholds reduce transfusion exposure modestly with no detectable effect on mortality or neurodevelopmental impairment at 18–26 months.
Neonatal hydrocortisone treatment in preterm infants at high risk for bronchopulmonary dysplasia does not improve school-age functional outcomes, highlighting the persistent burden of developmental impairment despite intervention.
Secondary analysis of the PENUT trial found that acute kidney injury (AKI) in infants born at 24–27 weeks’ gestation is independently associated with death or moderate to severe neurodevelopmental impairment at 22–26 months’ corrected
This study reveals the heterogeneous genetic architecture of impulsivity, uncovering diverse biological pathways linking it to neurodevelopment and psychopathology across the lifespan.
This article explores the link between prenatal and early postnatal lead exposure and adult anxiety and depression, emphasizing critical exposure windows and long-term mental health implications.
This study reveals that although individuals born preterm face higher risks of lower educational attainment, sociodemographic factors have a greater impact on long-term educational outcomes than prematurity itself.
