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Maternal Vaccination and Infant Whole-Cell Pertussis Series Synergize for Superior Mucosal Immunity
Infectious Diseasesmaternal vaccinationMucosal Immunity

Maternal Vaccination and Infant Whole-Cell Pertussis Series Synergize for Superior Mucosal Immunity

By MedXY|Jan 24, 2026

A phase 4 trial in The Gambia reveals that maternal Tdap-IPV vaccination provides early mucosal IgG to infants, while the DTwP primary series induces significantly stronger mucosal antibody and T-cell responses than DTaP, despite maternal a

A Breath of Protection: How a New Nasal Vaccine Could Stop Whooping Cough in its Tracks
Infectious DiseasesMucosal Immunity

A Breath of Protection: How a New Nasal Vaccine Could Stop Whooping Cough in its Tracks

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By MedXY|Jan 13, 2026

A groundbreaking clinical trial reveals that a novel nasal vaccine, BPZE1, can prevent Bordetella pertussis colonization, offering a potential solution to the transmission gaps in current whooping cough immunization programs.

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