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Analysis of 1,983 high-certainty DILI cases over two decades reveals shifting drug causes, declining severity, increased herbal and oncology-related cases, and higher mortality among elderly, patients with chronic liver disease, and oncolog
This study analyzes U.S. traumatic spinal cord injury mortality trends from 1999 to 2024, revealing stable overall rates but notable demographic disparities and pandemic-related mortality increases, highlighting the need for targeted preven
A U.S. mortality analysis from 1999 to 2020 found increasing deaths from status epilepticus after 2007, with marked disparities by age, sex, race/ethnicity, and region.
A landmark 20-year analysis of over 200,000 mechanically ventilated ARDS patients reveals a striking paradox—mortality declined during the ICD-9 era but increased after ICD-10 adoption, challenging assumptions about ARDS outcomes and highli
A retrospective study across 29 European countries reveals that mortality from haemophagocytic lymphohistiocytosis (HLH) increased significantly between 2011 and 2021, with notable bimodal age peaks and geographical disparities suggesting w
A large-scale study of over 300,000 ANZ ICU patients reveals that sepsis mortality plummeted from 28% to 11% between 2000 and 2020, followed by a concerning 0.9% annual increase through 2023, highlighting both clinical triumphs and emerging
From 2010 to 2019, NCD mortality declined in 80% of countries worldwide, driven primarily by reductions in circulatory diseases, with notable regional and cause-specific heterogeneity and slower progress than the previous decade.
A 15-year observational study of over 45,000 TBI patients reveals a significant increase in hospital mortality and a tripling of life-sustaining therapy withdrawal, alongside rising rates of hypoxaemia, raising urgent questions about ethica
This observational study reveals stable global biliary tract cancer mortality rates over two decades, with a striking rise in intrahepatic cholangiocarcinoma mortality, underscoring the need for targeted screening and management strategies.
