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Personalized Anti-Inflammatory Diet Modulates Gut Microbiome and Metabolome to Alleviate Osteoarthritis Pain

A 4-week anti-inflammatory dietary intervention in knee osteoarthritis patients led to targeted shifts in gut microbiota and metabolite profiles associated with significant pain reduction, highlighting the potential of microbiome-informed n

Sep 16, 2025
Clinical Updates

Recent Advances in Dihydroberberine Research: Pharmacokinetics, Mechanisms, and Clinical Potential

This review synthesizes the latest 5-year evidence on dihydroberberine, highlighting improved bioavailability over berberine, mechanistic insights from metabolic and network pharmacology studies, and its promising clinical applications in m

Aug 24, 2025
Diabetes & Endocrinology

Predicting Long-Term Mortality: Insights from a Multi-Metabolite Signature in the PREDIMED Trial

A study identified a robust plasma multi-metabolite signature that predicts long-term all-cause mortality in participants from the PREDIMED trial and several US cohorts, providing new insights into metabolic biomarkers.

Aug 11, 2025
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Most read

  1. 01Intimate Health

    Five Benefits for Women Continuing Sexual Activity After Menopause

  2. 02Intimate Health

    Why Some Women Have a Strong Sex Drive—And Why Men Shouldn't Worry About It

  3. 03Nursing & care

    How often should a couple have sex?

  4. 04Cardiology

    Precision Medicine for Long QT Syndrome Type 2: Lumacaftor Corrects Trafficking Defects and Shortens QT Interval

  5. 05General Surgery

    Optimizing Postoperative Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Comparing the 5x-Multiplier and 3-Tier Models

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