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Genetic Testing in Endometrial Cancer: Prevalence of Pathogenic Germline Variants and Implications for Clinical Practice in a Diverse Community Cohort

In a large, diverse cohort of women with endometrial cancer, 11.9% harbored pathogenic germline variants, including Lynch syndrome and homologous recombination deficiency-related mutations. Testing at diagnosis identified most Lynch syndrom

Oct 6, 2026
Gastroenterology

Surveillance Colonoscopy in Lynch Syndrome: Impact on Colorectal Cancer Outcomes in a National NHS Cohort

This national NHS cohort study evaluates how adherence to colonoscopy surveillance affects colorectal cancer incidence and mortality among Lynch syndrome patients, revealing decreased mortality despite unchanged incidence, raising implicati

Aug 11, 2026

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