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Clinical Utility of a 30% Reduction in VCTE-Derived Liver Stiffness Measurement for Identifying Histologic Improvement in Metabolic Dysfunction-Associated Steatohepatitis
Clinical Updatesliver stiffness measurementVCTE

Clinical Utility of a 30% Reduction in VCTE-Derived Liver Stiffness Measurement for Identifying Histologic Improvement in Metabolic Dysfunction-Associated Steatohepatitis

By MedXY|Sep 6, 2026

This review examines the clinical relevance of a ≥30% decrease in VCTE-derived liver stiffness in predicting fibrosis regression in MASH, highlighting modest predictive accuracy and the need for improved biomarkers.

Longitudinal Weight Changes in MASLD: Impact on Liver Outcomes and Disease Progression
Diabetes & Endocrinologyobesity
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MASLD

Longitudinal Weight Changes in MASLD: Impact on Liver Outcomes and Disease Progression

By MedXY|Aug 19, 2026

This study reveals that weight gain exceeding 5% in MASLD patients increases liver-related event risks and liver stiffness, whereas weight loss improves liver stiffness and may reduce adverse outcomes, especially with obesity reversal.

Validating Liver Stiffness Measurement as a Prognostic Tool in Primary Sclerosing Cholangitis: Insights from the Prospective FICUS Cohort
Gastroenterologytransplant-free survivalviêm ống mật xơ cứng nguyên phát

Validating Liver Stiffness Measurement as a Prognostic Tool in Primary Sclerosing Cholangitis: Insights from the Prospective FICUS Cohort

By MedXY|Aug 13, 2026

This prospective study confirms that liver stiffness measurement (LSM) by Fibroscan® effectively predicts transplant-free survival in primary sclerosing cholangitis (PSC), highlighting both static and dynamic assessments as powerful risk st

Liver Stiffness Measurements as Prognostic Tools in Primary Sclerosing Cholangitis: Insights from the Prospective FICUS Cohort
Gastroenterologyviêm ống mật xơ cứng nguyên phátliver stiffness measurement

Liver Stiffness Measurements as Prognostic Tools in Primary Sclerosing Cholangitis: Insights from the Prospective FICUS Cohort

By MedXY|Aug 7, 2026

This prospective study confirms that liver stiffness measurements by Fibroscan® strongly predict transplant-free survival in primary sclerosing cholangitis patients, validating both static values and dynamic changes as vital prognostic mark

Long-Term Real-World Effectiveness, Safety, and Liver Stiffness Changes with Obeticholic Acid in Primary Biliary Cholangitis
Gastroenterologycirrhosisliver stiffness measurement

Long-Term Real-World Effectiveness, Safety, and Liver Stiffness Changes with Obeticholic Acid in Primary Biliary Cholangitis

By MedXY|Oct 28, 2025

This study confirms the sustained effectiveness and safety of obeticholic acid (OCA) in primary biliary cholangitis (PBC) over a 2-year median follow-up, highlighting its impact on liver stiffness and fibrosis progression, especially in bio

Liver Stiffness Measurement vs. Biochemical Response in Primary Biliary Cholangitis: Predicting Liver Decompensation with Precision
GastroenterologyBiochemical Responsehepatic decompensation

Liver Stiffness Measurement vs. Biochemical Response in Primary Biliary Cholangitis: Predicting Liver Decompensation with Precision

By MedXY|Oct 28, 2025

In primary biliary cholangitis, liver stiffness measurement (LSM) outperforms biochemical response in predicting first hepatic decompensation, emphasizing LSM’s pivotal role in clinical risk stratification despite frequent discordance

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