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Low-Normal Hemoglobin Concentrations and Clinical Outcomes in Heart Failure: Rethinking WHO Anemia Thresholds

This review synthesizes current evidence on hemoglobin thresholds in heart failure, highlighting that optimal prognosis is associated with hemoglobin levels higher than WHO anemia cutoffs, with clinical implications for management and iron

Aug 30, 2026
news

Rising Burden of Anemia and Iron Deficiency Among U.S. Nonpregnant Women of Reproductive Age: Insights from NHANES 1999–2023

Analysis of NHANES data reveals increasing anemia and iron deficiency anemia rates among nonpregnant U.S. women aged 20-45 from 1999 to 2023, with persistently high iron deficiency prevalence.

Aug 18, 2026Sign in to read
Cardiology

Redefining Iron Deficiency in Heart Failure: Why TSAT and Serum Iron Outperform Ferritin for Prognosis

Recent large-scale studies, including HEART-FID and major national registries, demonstrate that transferrin saturation (TSAT) and serum iron levels are more accurate predictors of functional capacity and mortality in heart failure than trad

Dec 26, 2025
Anesthesiology

Preoperative Anaemia Is Common and Multifactorial: Iron Deficiency Dominates but B12 and Folate Shortfalls Matter

The ALICE international cohort found 31.7% prevalence of preoperative anaemia in major surgery patients; iron deficiency accounted for 55% of confirmed causes, with notable contributions from vitamin B12 and folate deficiencies. Broader pre

Nov 30, 2025
Clinical Updates

Ferritin-Guided Iron Supplementation in Blood Donors: Evidence Synthesis and Clinical Implications from the FORTE Trial and Related Studies

Iron supplementation guided by ferritin levels effectively mitigates iron deficiency and anaemia in regular blood donors, offering a practical alternative or adjunct to extending donation intervals.

Sep 20, 2025

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