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In the four-arm SleepCARE trial of 219 women receiving breast cancer chemotherapy, brief CBT-I significantly improved insomnia while bright light therapy did not beat sleep hygiene education. Neither helped fatigue, and combining the two added burden without benefit.
In patients with OSA and elevated blood pressure, comorbid insomnia is linked to a significantly greater blood pressure reduction following short-term CPAP therapy, highlighting the clinical importance of addressing both sleep disorders.
A randomized clinical trial demonstrates that smartphone-based ecological momentary assessment (EMA) is significantly more sensitive than retrospective questionnaires in detecting the daytime clinical benefits of suvorexant, particularly re
A multicenter trial finds low-dose amitriptyline non-inferior to CBT-I for comorbid insomnia based on a liberal margin. However, CBT-I yielded superior clinical response rates and fewer side effects, reinforcing its status as the gold-stand
A randomized trial comparing Tai Chi and CBT-I in adults over 50 found that while CBT-I offers faster relief, Tai Chi achieves non-inferior results at 12 months post-intervention, suggesting it is a viable long-term strategy for insomnia ma
This article analyzes a nationwide decentralized RCT and a systematic meta-analysis to evaluate the efficacy of digital Cognitive Behavioral Therapy for Insomnia (CBT-I), highlighting its role as a scalable, evidence-based first-line treatm
A 2025 Cochrane review of 21 RCTs (2431 participants) finds cognitive behavioural therapy for insomnia (CBT‑I) yields modest improvements in self‑reported insomnia and sleep quality in people with cancer versus inactive controls or aerobic
A 2025 Cochrane review (5 RCTs, 402 patients, mainly women with breast cancer) finds very low- to moderate-certainty evidence that acupuncture delivers small, uncertain sleep diary benefits versus sham or inactive controls and is probably l
A prospective observational study of 37 adults with insomnia reports high adherence and no serious adverse events with 40 Hz light–sound flicker and sleep-diary improvements in sleep onset, arousals, and total sleep time; limitations includ
This meta-analysis confirms that cognitive behavioral therapy for insomnia (CBT-I) is an effective, well-accepted treatment improving sleep outcomes across diverse chronic diseases, with minimal adverse effects and potential for broad clini
A double-blind, randomized trial demonstrates that electrical vestibular stimulation (VeNS) significantly reduces insomnia severity and improves quality of life in adults, highlighting a novel non-pharmacological treatment option.
A randomized clinical trial reveals older adults with insomnia have heightened depressive responses to inflammatory challenge, underscoring the need for targeted depression monitoring and prevention strategies in this vulnerable population.
This article addresses common myths about insomnia and provides practical tips for achieving better sleep hygiene.
Insomnia affects millions worldwide, especially older adults. This article explores nine common misconceptions about insomnia, their impacts, and science-backed strategies for better sleep and health.
A recent Mendelian randomization study suggests bidirectional causal links between specific gut bacteria and insomnia, highlighting potential microbiome-based interventions, though causality remains debated among experts.
A Swedish cohort study reveals increased use of hypnotics, anxiolytics, and antidepressants prior to autoimmune Addison’s diagnosis, highlighting mental health symptoms as early signs and the common occurrence of insomnia in AAD patients.
Discover five science-backed, free methods to enhance sleep quality and wake up refreshed—no medication or costly therapies required.
Discover five evidence-based, cost-free strategies to improve your sleep quality, from daily routines to mindset shifts, for faster, deeper rest.
Discover the science and practice behind the 4-7-8 breathing technique, touted as a natural remedy for insomnia, and learn how to use it effectively for better sleep.
Prepare for travel with essential medications to handle chronic conditions, motion sickness, insomnia, infections, and more.
