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Diabetes & Endocrinology

Hippocampal Structural Alterations and White Matter Changes in Congenital Adrenal Hyperplasia: Insights into Sex-Specific Brain Vulnerabilities

This study reveals significant hippocampal subfield volume reductions and white matter impairments in patients with congenital adrenal hyperplasia, highlighting sex-specific differences that could influence cognitive outcomes and treatment

Oct 23, 2026
Neurology

Unraveling the Neurobiological Pathways Linking Childhood Trauma to Bipolar Disorder: Insights from the ENIGMA Consortium

An international study reveals that childhood trauma’s association with bipolar disorder is partially mediated by brain morphology changes, particularly in hippocampal volume and frontal cortical thickness.

Aug 12, 2026Sign in to read
Neurology

Brain Imaging Biomarkers and Cognitive Outcomes in a Multidomain Lifestyle Intervention: The POINTER Imaging Ancillary Study

The POINTER Imaging study found no overall brain biomarker changes from a structured lifestyle intervention, but participants with lower baseline hippocampal volume showed greater cognitive benefit, suggesting imaging may help identify who

Jun 17, 2026Sign in to read
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Neurology

High‑Intensity Interval Training Fails to Rescue Hippocampal Integrity in Adults With Cannabis Use Disorder — but Exercise Is Feasible and May Reduce Craving

A randomized trial in adults with moderate–severe cannabis use disorder found 12 weeks of supervised HIIT did not improve a composite MRI measure of hippocampal integrity versus strength/resistance training; exercise participation was feasi

Nov 14, 2025

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