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Targeted Gut-Liver Axis Modulation: The Therapeutic Potential of Gut-Restricted LXR Agonists in Short Bowel Syndrome
Clinical UpdatesHepatoprotectionHội chứng ruột ngắn

Targeted Gut-Liver Axis Modulation: The Therapeutic Potential of Gut-Restricted LXR Agonists in Short Bowel Syndrome

By MedXY|Mar 11, 2026

This review explores the development of WUSTL0717, a gut-restricted LXR agonist that mitigates liver injury in short bowel syndrome by leveraging the intestinal HDL-ApoA1 pathway without inducing systemic metabolic complications.

Silymarin in Clinical Medicine: A Decade of Therapeutic Advances and Future Disease Targets
Clinical UpdatesHepatoprotectionmetabolic diseases
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Silymarin in Clinical Medicine: A Decade of Therapeutic Advances and Future Disease Targets

By MedXY|Oct 4, 2025

Comprehensive review of recent decade research on silymarin elucidates its antioxidant, anti-inflammatory, and hepatoprotective effects, highlighting promising clinical applications in metabolic diseases, neurodegeneration, liver disorders,

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