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Connectivity- vs Scalp-Based Targeting of Accelerated Transcranial Magnetic Stimulation for Depression: A Randomized Clinical Trial
Neurologytranscranial magnetic stimulationdepression

Connectivity- vs Scalp-Based Targeting of Accelerated Transcranial Magnetic Stimulation for Depression: A Randomized Clinical Trial

By MedXY|Aug 10, 2026

This randomized trial compared connectivity-based versus scalp-based targeting of accelerated TMS in treatment-resistant depression, showing greater antidepressant effects with individualized connectivity-guided targeting.

Connectivity as a Universal Predictor of Tau Progression in Atypical Alzheimer’s Disease: A Multicentre Evidence Synthesis
Clinical UpdatesAlzheimer's diseaseFunctional Connectivity

Connectivity as a Universal Predictor of Tau Progression in Atypical Alzheimer’s Disease: A Multicentre Evidence Synthesis

By MedXY|Dec 13, 2025

Functional connectivity reliably predicts spatial and temporal tau propagation patterns across atypical Alzheimer’s disease variants, underpinning personalized approaches to diagnosis and therapy.

Functional Connectivity as a Predictor of Transdiagnostic Treatment Outcomes in Internalizing Psychopathologies: Advances and Clinical Implications
Clinical UpdatesFunctional ConnectivityPrecision Psychiatry

Functional Connectivity as a Predictor of Transdiagnostic Treatment Outcomes in Internalizing Psychopathologies: Advances and Clinical Implications

By MedXY|Oct 27, 2025

Whole-brain functional connectivity patterns predict multidimensional treatment outcomes across internalizing psychopathologies and various therapies, highlighting neural network biomarkers for personalized psychiatric care.

Brain Connectome Modulates the Impact of Adverse Childhood Experiences on Mental Health in Preadolescents
newsAdverse Childhood ExperiencesFunctional Connectivity

Brain Connectome Modulates the Impact of Adverse Childhood Experiences on Mental Health in Preadolescents

By MedXY|Oct 9, 2025

This cohort study reveals that whole-brain functional connectivity alters the link between adverse childhood experiences and psychiatric disorders in children, particularly for threat-related exposures and females, suggesting a neurobiologi

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