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This study reveals that family history significantly elevates postpartum venous thromboembolism risk in primiparous women, with risk proportional to genetic relatedness and number of affected relatives.
A nationwide cohort study reveals that in IBD patients, colorectal cancer risk increases notably with multiple affected relatives, challenging current guidelines prioritizing early-onset family history for surveillance.
A cohort study demonstrates increased major cardiovascular event risk in first-degree relatives of individuals with high plasma lipoprotein(a), supporting cascade screening for targeted prevention.
A large real-world registry study shows that ovarian cancer patients aged 70 and older still carry clinically actionable germline variants, often without a reported family history, supporting broader age-inclusive genetic testing.
This study identifies key germline variants and demonstrates how combining genetic data with family history improves personalized prostate cancer risk assessment in men of African ancestry, guiding future screening strategies.
This study evaluates cumulative breast cancer risks among US women based on pathogenic variant status and family history, revealing significant risk stratification that informs personalized screening and prevention.
