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A single-center study demonstrates that an AI pipeline for CT-based lymph node segmentation and extranodal extension classification significantly improves prognostic accuracy for HPV-positive oropharyngeal cancer compared to traditional rad
A multicenter cohort study shows adjuvant chemoradiotherapy improves disease-free and overall survival for oral cavity SCC patients with major extranodal extension (>2 mm) but provides no clear benefit for those with minor ENE (≤2 mm).
This multinational real-world study reveals limited sensitivity and prognostic value of radiologic extranodal extension (iENE) in HPV-positive oropharyngeal cancer, highlighting the enhanced accuracy with combined CT and MRI and the need fo
Imaging-based extranodal extension (iENE) in HPV-positive oropharyngeal cancer predicts higher rates of distant metastases and decreased progression-free survival, highlighting its prognostic significance and potential role in refining stag
A new clinical TNM staging proposal incorporating imaging-detected extranodal extension (iENE) refines prognostic accuracy in HPV-positive oropharyngeal carcinoma, aiding risk stratification and future treatment strategies.
An AI-driven model accurately detects imaging-based extranodal extension in HPV-positive oropharyngeal cancer from CT scans, improving outcome prediction beyond expert radiologist assessments and identifying patients at higher risk of poore
This multicenter study clarifies that adjuvant chemotherapy improves survival outcomes in oral cavity squamous cell carcinoma with major extranodal extension but offers no clear benefit in cases with minor extranodal extension.
