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Circulating extracellular vesicles carrying PD-1, PD-L1, and CTLA-4 can non-invasively predict responses and early resistance to immune checkpoint inhibitors in advanced hepatocellular carcinoma, improving patient stratification and managem
Severe burns alter extracellular vesicle protein cargo, revealing coordinated immune and neuronal signaling changes that drive inflammation and healing responses, suggesting novel biomarker and therapeutic avenues.
A new multimodal study links regular physical activity to lower chronic pancreatitis risk and identifies muscle-derived extracellular vesicles as a plausible mechanism limiting pancreatic inflammation, fibrosis, and ferroptosis.
This review synthesizes recent evidence from the UK Biobank and molecular studies demonstrating that physical activity, particularly resistance exercise, restrains chronic pancreatitis by delivering muscle-derived extracellular vesicles tha
A five-RNA extracellular vesicle signature showed strong diagnostic performance for chronic pancreatitis and may also reflect acinar-to-ductal metaplasia and disease-related metabolic features.
Intensive treadmill rehabilitation in Parkinson’s disease alters the biochemical composition of circulating extracellular vesicle-like particles, particularly increasing carotenoid content, which correlates with improved gait paramete