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exercise capacity

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Cardiology

Sotatercept’s Multifaceted Role in Enhancing Exercise Capacity in Pulmonary Arterial Hypertension

Sotatercept improves exercise tolerance in pulmonary arterial hypertension through pulmonary vascular remodeling, systemic decongestion with hemoconcentration, improved right ventricular-pulmonary artery coupling, enhanced cardiac output re

Aug 12, 2026
Cardiology

Exercise Performance With Aficamten vs Metoprolol in Obstructive Hypertrophic Cardiomyopathy: Insights from the MAPLE-HCM Phase 3 Randomized Trial

The MAPLE-HCM trial demonstrates aficamten monotherapy significantly outperforms metoprolol in improving exercise capacity, hemodynamics, and patient-reported outcomes in obstructive hypertrophic cardiomyopathy (oHCM), supporting aficamten

Jun 28, 2026Sign in to read
General Surgery

Riociguat Continuation After Balloon Pulmonary Angioplasty Preserves Exercise Capacity in Inoperable CTEPH: Insights from the THERAPY-HYBRID-BPA Trial

The THERAPY-HYBRID-BPA study demonstrates that continuing riociguat after balloon pulmonary angioplasty maintains exercise capacity in patients with inoperable chronic thromboembolic pulmonary hypertension without increasing adverse events.

Sep 19, 2025Sign in to read
Clinical Updates

Minimal Equipment Pulmonary Rehabilitation Matches Specialized Gym-Based Programs: New RCT Evidence

A large randomized clinical trial demonstrates that pulmonary rehabilitation using minimal equipment is noninferior to gym-based programs with specialist equipment for improving exercise capacity and quality of life in chronic respiratory d

Aug 24, 2025Sign in to read
Neurology

Enhancing Exercise Capacity Through Non-Invasive Vagus Nerve Stimulation: Evidence from a Randomized Controlled Trial

A randomized trial demonstrates that non-invasive transcutaneous vagus nerve stimulation improves peak oxygen uptake and exercise performance in healthy volunteers, highlighting its potential as a safe and scalable method to boost cardiores

Aug 13, 2025

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