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Unraveling the Neurobiological Pathways Linking Childhood Trauma to Bipolar Disorder: Insights from the ENIGMA Consortium
Neurologybrain morphologycortical thickness

Unraveling the Neurobiological Pathways Linking Childhood Trauma to Bipolar Disorder: Insights from the ENIGMA Consortium

By MedXY|Aug 12, 2026

An international study reveals that childhood trauma’s association with bipolar disorder is partially mediated by brain morphology changes, particularly in hippocampal volume and frontal cortical thickness.

Normative Modeling Exposes Hidden Individual Variability in Traumatic Brain Injury: A New Frontier for Personalized Neuroimaging Assessment
Neurologybrain morphologycortical thickness

Normative Modeling Exposes Hidden Individual Variability in Traumatic Brain Injury: A New Frontier for Personalized Neuroimaging Assessment

By MedXY|Apr 5, 2026

A landmark study of 631 participants reveals that normative modeling uncovers substantial individual heterogeneity in brain morphology following traumatic brain injury that conventional group-based analyses miss, with every patient exhibiti

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