Clinical Diagnostics

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Clinical Factors Associated With Discordant Plasma P-Tau217 and Established Alzheimer Disease Biomarkers: Implications for Diagnosis and Management

This review synthesizes evidence on clinical and biological factors linked to discordance between plasma p-tau217 and standard AD biomarkers, highlighting implications for diagnosis, patient stratification, and future biomarker development.

Oct 7, 2026

Clinical Updates

Comparative Diagnostic Performance of Global Thyroid Ultrasound Risk Stratification Systems: The Impact of Nodule Size and Lexicon Standardization

This review synthesizes findings from a large-scale comparison of five major thyroid ultrasound risk stratification systems (RSSs), evaluating how nodule size and standardized lexicon influence sensitivity, specificity, and unnecessary biop

Mar 8, 2026Sign in to read

Emergency Medicine

Age-Adjusted D-Dimer Cutoffs Safely Rule Out Deep Vein Thrombosis: Results from the ADJUST-DVT Trial

The ADJUST-DVT study confirms that an age-adjusted D-dimer cutoff (age × 10 µg/L) safely increases the number of patients in whom deep vein thrombosis can be ruled out without imaging, particularly benefiting patients over 75 years of age.

Jan 6, 2026Sign in to read