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MedXY AI/MedXY News/Tag: cerebral small vessel disease
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Metabolic Signatures and Causal Markers in MRI-Confirmed Lacunar Stroke: Insights from Observational and Mendelian Randomization Analyses
NeurologyMendelian Randomizationcerebral small vessel disease

Metabolic Signatures and Causal Markers in MRI-Confirmed Lacunar Stroke: Insights from Observational and Mendelian Randomization Analyses

By MedXY|Sep 15, 2026

This study identifies glycine and specific lipid cholesterol proportions as metabolomic markers causally linked to lacunar stroke subtypes, enhancing understanding of cerebral small vessel disease pathogenesis and potential biomarkers.

Early Detection of Cerebral Small Vessel Disease: Diffusion MRI Reveals a Decade-Long Preclinical Phase Before White Matter Hyperintensities
Neurology
cerebral small vessel disease
diffusion MRI

Early Detection of Cerebral Small Vessel Disease: Diffusion MRI Reveals a Decade-Long Preclinical Phase Before White Matter Hyperintensities

By MedXY|Sep 8, 2026

Diffusion MRI detects microstructural brain changes up to 16 years before white matter hyperintensities appear, offering a valuable early window for cerebral small vessel disease intervention and improved risk stratification.

DWI-Positive Lesions in Acute Intracerebral Hemorrhage: Insights into Cerebral Small Vessel Disease and Prognosis
Neurologyfunctional outcomeDiffusion-weighted imaging

DWI-Positive Lesions in Acute Intracerebral Hemorrhage: Insights into Cerebral Small Vessel Disease and Prognosis

By MedXY|Aug 15, 2026

DWI-positive lesions in acute intracerebral hemorrhage patients correlate with cerebral small vessel disease markers and predict poorer 6-month outcomes, with lesion distribution varying by small vessel disease subtype.

Basal Ganglia Perivascular Spaces: A Dual-Risk Biomarker for Ischemic Stroke and Major Bleeding in Antithrombotic Therapy
Neurologycerebral small vessel diseaseLiệu pháp chống huyết khối

Basal Ganglia Perivascular Spaces: A Dual-Risk Biomarker for Ischemic Stroke and Major Bleeding in Antithrombotic Therapy

By MedXY|Mar 27, 2026

A large-scale prospective study identifies high basal ganglia perivascular space (BGPVS) burden as a significant predictor of both major bleeding and ischemic stroke in patients on antithrombotic regimens, offering a new imaging biomarker f

High Basal Ganglia Perivascular Space Burden Predicts Both Ischemic Stroke and Major Bleeding in Antithrombotic Users
Neurologycerebral small vessel diseaseLiệu pháp chống huyết khối

High Basal Ganglia Perivascular Space Burden Predicts Both Ischemic Stroke and Major Bleeding in Antithrombotic Users

By MedXY|Mar 22, 2026

A large prospective study reveals that a high burden of basal ganglia enlarged perivascular spaces (BGPVSs) significantly increases the risk of both ischemic stroke and major bleeding in patients on antithrombotic therapy, positioning BGPVS

Midlife Plasma GFAP as a Long-Term Sentinel for Cerebral Small Vessel Disease: A Decadal Prospective Study
Neurologybiomarkerscerebral small vessel disease

Midlife Plasma GFAP as a Long-Term Sentinel for Cerebral Small Vessel Disease: A Decadal Prospective Study

By MedXY|Jan 6, 2026

Elevated plasma glial fibrillary acidic protein (GFAP) in middle age independently predicts the progression of cerebral small vessel disease MRI markers nearly a decade later, suggesting its potential as an early-stage prognostic biomarker

Enlarged Perivascular Spaces as Early Neurovascular Biomarkers in Alzheimer Disease: Integrating Serum and MRI Findings from Multicultural Cohorts
Clinical UpdatesAlzheimer diseasebiomarkers

Enlarged Perivascular Spaces as Early Neurovascular Biomarkers in Alzheimer Disease: Integrating Serum and MRI Findings from Multicultural Cohorts

By MedXY|Oct 20, 2025

Enlarged perivascular spaces (EPVS) correlate with serum biomarkers of neuroinflammation and amyloid pathology and associate with cognitive impairment, supporting their role as early MRI markers for Alzheimer disease (AD) vascular contribut

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