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Aggressive LDL-C Lowering Mitigates Neoatherosclerosis Risk: Insights from the CONNECT Trial
CardiologyCardiologyLDL-C

Aggressive LDL-C Lowering Mitigates Neoatherosclerosis Risk: Insights from the CONNECT Trial

By MedXY|Dec 24, 2025

This secondary analysis of the CONNECT trial demonstrates that achieving guideline-endorsed LDL-C levels significantly lowers the risk of neoatherosclerosis three years post-DES implantation in STEMI patients, underscoring the vital role of

Obstructive Coronary Artery Disease Does Not Diminish Long-Term Health Status or Clinical Efficacy After TAVR: 3-Year Insights from SCOPE I
CardiologyCardiologyclinical trials

Obstructive Coronary Artery Disease Does Not Diminish Long-Term Health Status or Clinical Efficacy After TAVR: 3-Year Insights from SCOPE I

By MedXY|Dec 21, 2025

A post hoc analysis of the SCOPE I trial reveals that obstructive coronary artery disease (CAD) does not significantly impact 3-year survival or patient-reported health status following TAVR, questioning the routine necessity of periprocedu

Prophylactic Pacemakers After TAVR: Low Pacing Burden Raises Questions on Routine Use
CardiologyCardiologyTAVR

Prophylactic Pacemakers After TAVR: Low Pacing Burden Raises Questions on Routine Use

By MedXY|Dec 17, 2025

One-fourth of TAVR patients receive prophylactic pacemakers, but most have minimal pacing needs at 30 days.

PROMOTE Study Validates Algorithm for Conduction Disturbance Management After TAVR
CardiologyCardiologyConduction Disturbances

PROMOTE Study Validates Algorithm for Conduction Disturbance Management After TAVR

By MedXY|Dec 17, 2025

A prospective multicenter study confirms that a prespecified algorithm for conduction disturbance management after TAVR is safe, with low sudden cardiac death risk but persistent high pacemaker rates.

Safety and Efficacy of the Trilogy Transcatheter Aortic Valve for High-Risk Native Aortic Regurgitation: Insights from the ALIGN-AR Studies
CardiologyCardiologyclinical outcomes

Safety and Efficacy of the Trilogy Transcatheter Aortic Valve for High-Risk Native Aortic Regurgitation: Insights from the ALIGN-AR Studies

By MedXY|Nov 28, 2025

The ALIGN-AR studies demonstrate that transcatheter aortic valve implantation using the Trilogy valve is a safe and effective treatment for symptomatic native moderate-to-severe or severe aortic regurgitation in patients at high surgical ri

AI-Augmented Screening Triples Detection Yield of Transthyretin Cardiac Amyloidosis in a Multisite Real-World Trial
AIartificial intelligenceATTR-CM

AI-Augmented Screening Triples Detection Yield of Transthyretin Cardiac Amyloidosis in a Multisite Real-World Trial

By MedXY|Nov 18, 2025

An AI-driven screening program (ATTRACTnet) applied to ECG, echocardiography, demographics and orthopedic history substantially increased case detection of transthyretin cardiac amyloidosis (ATTR‑CM) and led to rapid treatment initiation in

Innovations in Atrial Septal Defect Closure: Comparing Bioresorbable and Metallic Occluders
CardiologyCardiologyDevice Safety

Innovations in Atrial Septal Defect Closure: Comparing Bioresorbable and Metallic Occluders

By MedXY|Oct 24, 2025

This article reviews a landmark randomized trial demonstrating that bioresorbable occluders are noninferior to metallic ones in ASD closure, with implications for improved patient outcomes and device management.

Cardiologists and Lifestyle Medicine: Bridging the Gap Between Recommendation and Practice
CardiologyCardiologydiet

Cardiologists and Lifestyle Medicine: Bridging the Gap Between Recommendation and Practice

By MedXY|Oct 5, 2025

A recent survey reveals that most US cardiologists inconsistently adhere to lifestyle recommendations, especially dietary and physical activity guidelines, despite endorsing them for cardiovascular health.

Marshall-Plan Ablation Strategy Versus Pulmonary Vein Isolation in Persistent AF
Cardiologyatrial fibrillationCardiology

Marshall-Plan Ablation Strategy Versus Pulmonary Vein Isolation in Persistent AF

By MedXY|Oct 3, 2025

This study compares the effectiveness of the Marshall-Plan ablation strategy against pulmonary vein isolation for treating persistent atrial fibrillation.

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