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Preserved Endogenous Insulin Production Significantly Reduces Diabetic Ketoacidosis Risk in Type 1 Diabetes
Diabetes & Endocrinologytype 1 diabetesEndogenous Insulin

Preserved Endogenous Insulin Production Significantly Reduces Diabetic Ketoacidosis Risk in Type 1 Diabetes

By MedXY|Sep 8, 2026

Detectable C-peptide levels indicating residual insulin production strongly correlate with lower diabetic ketoacidosis risk in type 1 diabetes, highlighting the importance of preserving beta-cell function for improved clinical outcomes.

Impact of Residual C-Peptide on Long-Term Outcomes in Type 1 Diabetes: Insights from the Scottish Cohort
Diabetes & Endocrinologydiabetic complicationstype 1 diabetes

Impact of Residual C-Peptide on Long-Term Outcomes in Type 1 Diabetes: Insights from the Scottish Cohort

By MedXY|Aug 11, 2026

This study highlights that higher baseline and maintained C-peptide levels in type 1 diabetes are linked to reduced risks of acute complications and retinopathy, underscoring the importance of preserving endogenous insulin secretion.

Exploring Low-Dose Antithymocyte Globulin Therapy in Type 1 Diabetes: Real-World Insights Using Modified Quantitative Response of C-Peptide
Diabetes & Endocrinologyantithymocyte globulinbeta-cell preservation

Exploring Low-Dose Antithymocyte Globulin Therapy in Type 1 Diabetes: Real-World Insights Using Modified Quantitative Response of C-Peptide

By MedXY|Jul 14, 2026

This article examines real-world data on low-dose antithymocyte globulin in type 1 diabetes, assessing beta-cell function via a novel C-peptide modified quantitative response (mQR). Findings suggest feasibility, safety, and potential clinic

Early Detection of β-Cell Preservation in New-Onset Type 1 Diabetes: Insights from Serial Dried Blood Spot C-Peptide Sampling in the USTEKID Trial
Diabetes & EndocrinologyC-peptidetype 1 diabetes

Early Detection of β-Cell Preservation in New-Onset Type 1 Diabetes: Insights from Serial Dried Blood Spot C-Peptide Sampling in the USTEKID Trial

By MedXY|Jul 10, 2026

Serial dried blood spot C-peptide sampling detects early β-cell preservation in new-onset type 1 diabetes more sensitively than urine C-peptide-to-creatinine ratio or mixed-meal tolerance test.

Beta Cell Glucose Sensitivity May Predict Response to New-Onset Type 1 Diabetes Therapies
Diabetes & Endocrinologybeta cell glucose sensitivityC-peptide

Beta Cell Glucose Sensitivity May Predict Response to New-Onset Type 1 Diabetes Therapies

By MedXY|Jun 3, 2026

A pooled analysis of nine type 1 diabetes trials found that beta cell glucose sensitivity may better predict response to disease-modifying therapy than C-peptide alone, helping identify patients most likely to benefit.

Revealing Metabolic Subtypes in Gestational Diabetes Using Dynamic OGTT-Derived C-Peptide Trajectories: Implications for Personalized Risk and Management
Clinical UpdatesBeta-cell functionC-peptide

Revealing Metabolic Subtypes in Gestational Diabetes Using Dynamic OGTT-Derived C-Peptide Trajectories: Implications for Personalized Risk and Management

By MedXY|Oct 4, 2025

Dynamic C-peptide patterns during OGTT uncover metabolic heterogeneity in GDM, identifying insulin-resistant women at risk for fetal overgrowth and normoglycemic women at risk for preeclampsia, suggesting improved stratified treatment beyon

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