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Prior Traumatic Brain Injury and Alzheimer Disease Blood Biomarkers: Diagnostic Challenges and Clinical Implications
Clinical UpdatesAlzheimer's diseaseamyloid beta

Prior Traumatic Brain Injury and Alzheimer Disease Blood Biomarkers: Diagnostic Challenges and Clinical Implications

By MedXY|Jul 1, 2026

This review examines the impact of traumatic brain injury on the accuracy of Alzheimer disease blood biomarkers, highlighting reduced diagnostic performance in TBI-affected populations and the implications for clinical interpretation.

Advances in Alzheimer’s Diagnosis: A Comprehensive Review of CSF and Blood Biomarkers
NeurologyAlzheimer's diseaseblood-based biomarkers
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Advances in Alzheimer’s Diagnosis: A Comprehensive Review of CSF and Blood Biomarkers

By MedXY|Oct 20, 2025

This article reviews a systematic meta-analysis of 15 cerebrospinal fluid and blood biomarkers for Alzheimer’s disease, highlighting robust diagnostic performance of core markers T-tau, P-tau, and Aβ42 in clinical practice and researc

Assessing the Role of Kidney Function in Alzheimer’s Disease Blood Biomarker Interpretation and Amyloid-β Positivity Prediction
NephrologyAlzheimer's diseaseamyloid-β positivity

Assessing the Role of Kidney Function in Alzheimer’s Disease Blood Biomarker Interpretation and Amyloid-β Positivity Prediction

By MedXY|Oct 20, 2025

Kidney function influences certain Alzheimer’s disease blood biomarker levels but, within normal to mild impairment ranges, does not improve prediction of amyloid-β positivity, supporting the clinical utility of blood biomarkers in AD

Unraveling Blood-Based Biomarkers in Neurodegenerative Diseases: Insights from the Young Finns Study on Intergenerational and Metabolic Influences
Internal Medicineamyloid betaAPOE ε4

Unraveling Blood-Based Biomarkers in Neurodegenerative Diseases: Insights from the Young Finns Study on Intergenerational and Metabolic Influences

By MedXY|Oct 20, 2025

This cohort study from the Young Finns Study elucidates factors influencing blood-based biomarkers for neurodegenerative diseases, highlighting age, APOE ε4 genotype, kidney function, metabolic parameters, and notable intergenerational asso

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