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Genetic variants in dilated cardiomyopathy confer differential arrhythmic risks, independent of traditional clinical parameters. Integrating recent registry data and molecular studies enhances risk stratification and informs tailored manage
The EXCALIBUR study reveals significant arrhythmia incidence in cardiac amyloidosis (CA), highlighting subtype-specific arrhythmic profiles linked to myocardial amyloid burden, guiding risk stratification and management.
This study reveals genotype-specific differences in atrial fibrillation (AF) risk among dilated cardiomyopathy (DCM) patients, highlighting LMNA mutations as a major predictor of incident AF and its association with worse clinical outcomes,
This article reviews a validated clinical risk model predicting arrhythmic events in patients with RYR2-mediated CPVT receiving beta-blockers, facilitating personalized management to reduce life-threatening arrhythmias.
Genetic variants enriched in individuals of African ancestry confer increased risk of cardiomyopathy and arrhythmias, with cardiovascular risk factors amplifying this risk. Large biobank studies enable reclassification of key variants and h
This article reviews how SLC4A3 gene mutations cause short QT syndrome by inducing intracellular alkalinization and altered ion channel currents, increasing arrhythmia risk, based on stem cell-derived cardiomyocyte models.
Continuous monitoring in heart failure patients revealed a high burden of arrhythmias linked to more interventions, hospitalizations, and heart failure events, but not altered by the study’s congestion-management strategy.
Continuous ICM monitoring in heart failure uncovered a high arrhythmia burden, including atrial fibrillation, bradyarrhythmia, and VT/VF, which was linked to more interventions, hospitalizations, and heart failure events.
Continuous implantable monitoring in heart failure revealed a high burden of arrhythmias, strongly linked to hospitalizations and treatment changes, but not reduced by protocol-directed congestion management.
Continuous ICM monitoring in heart failure found a high burden of atrial fibrillation, bradyarrhythmia, and VT/VF. Arrhythmias were linked to more interventions and higher hospitalization risk, but the congestion-management strategy did not
Background Fontan palliation has transformed the prognosis of children born with single-ventricle heart disease, allowing...
A multi-center study of 385 ARVC patients reveals that while Left Ventricular Late Gadolinium Enhancement (LV LGE) correlates with ventricular arrhythmias, it fails to provide incremental prognostic value beyond the established ARVC risk ca
The DECAF randomized trial challenges the traditional view of caffeine as a trigger for atrial fibrillation, demonstrating that coffee consumption significantly reduces arrhythmia recurrence after cardioversion compared to total abstinence.
A landmark Spanish study reveals that patients with ‘arrhythmic’ genotypes in dilated cardiomyopathy face a significantly higher risk of advanced heart failure events, including heart transplantation and VAD implantation, necess
In 718 patients with pathogenic/likely pathogenic LMNA variants, truncating variants carried higher risk of malignant ventricular arrhythmia independent of position, while missense variants in the tail domain and exons 7–12 had lower arrhyt
Smartwatches are transforming healthcare, from heart monitoring to early disease detection. But are they truly lifesavers—or can they mislead us? Discover the science, the myths, and the future of wearable health tech.
