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A large Tokyo case-crossover study found that short-term exposure to low ambient temperature increases acute heart failure admissions, especially in older adults, while patients with hypotensive presentations may be more vulnerable to heat.
Evidence reveals that both extreme cold and heat significantly trigger acute heart failure decompensation, with risk sensitivity varying by age and hemodynamic phenotype, necessitating targeted clinical prevention.
Kidney tubular damage biomarkers independently predict death and heart failure readmission in acute heart failure, highlighting novel risk stratification beyond traditional glomerular measures.
The TAP-IT trial found that additional thoracentesis in acute heart failure patients with pleural effusion did not improve days alive out of hospital, mortality, or length of stay compared to standard therapy alone.
Low-dose carperitide shows no significant benefit on long-term outcomes in acute heart failure, with evidence from randomized and large-scale cohort studies suggesting possible increased short-term risks compared to nitrates.
Combining CA125 with NT-proBNP significantly improves prediction of cardiovascular and all-cause mortality, as well as rehospitalization risk in patients with acute heart failure.