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This review elucidates the contrasting roles of ACADM-mediated fatty acid β-oxidation in atherosclerosis and abdominal aortic aneurysm, highlighting differential lipid metabolism and translational implications for diagnosis and therapy.
An epigenome-wide study reveals that DNA methylation markers linked to inflammatory pathways and blood lipid traits play a causal role in abdominal aortic aneurysm development, offering potential for improved risk prediction and therapeutic
This nationwide Dutch cohort study reveals sex- and age-specific differences in mortality, long-term survival, and postdischarge care after ruptured abdominal aortic aneurysm repair, emphasizing the need for tailored management in women.
Elevated plasma TMAO levels are associated with higher risk of abdominal aortic aneurysm development, rapid aneurysm growth, and need for surgical repair, providing a promising tool for risk stratification and personalized surveillance.
This 5-year prospective cohort study reveals that high-dose statin therapy significantly slows abdominal aortic aneurysm growth and reduces the risks of repair, rupture, and death in men, suggesting benefits beyond traditional cardiovascula
