Recent Mechanical Venous Thrombosis Risk Factors and Their Role in Young-Onset Cryptogenic Ischemic Stroke
cryptogenic ischemic strokemechanical risk factorsPatent Foramen Ovalevenous thrombosis risk factorsYoung Adults
Highlight
- Mechanical venous thrombosis risk factors (VTRFs) occurring within 14 days prior to stroke significantly increase the risk of cryptogenic ischemic stroke (CIS) in young adults aged 18–49.
- The association is particularly strong in younger adults (18–39 years) and in patients with clinically relevant patent foramen ovale (PFO).
- No significant association was found for VTRFs occurring more than 14 days before stroke or for thrombophilic blood markers.
- These findings suggest recent mechanical VTRFs may trigger stroke via venous thromboembolism and paradoxical embolism, highlighting opportunities for targeted prevention.
Study Background
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.