Validating the Patient’s Voice in Hidradenitis Suppurativa: A Systematic Review and Meta-Analysis of Patient-Reported Outcome Measures

MedXY Editorial Team•Mar 5, 2026•Clinical Updates

Of 15 unique HS-specific patient-reported outcome measures (PROMs) evaluated, only 7 currently meet the COSMIN criteria for recommendation based on content validity and psychometric evidence.
The 17-item Hidradenitis Suppurativa Quality of Life (HiSQOL-17) demonstrated the most robust internal consistency (pooled Cronbach α = 0.94) and strong construct validity.
Significant research gaps remain, particularly the total absence of studies evaluating measurement error for any HS-specific instrument.
Current evidence supports a shift from generic dermatology tools to disease-specific instruments to better capture the unique psychosocial and physical burden of HS.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.