Nicotine E-Cigarettes Show Higher Quit Rates Than Traditional Nicotine Replacement Therapy

Highlight

• Nicotine e-cigarettes (EC) demonstrate higher smoking quit rates than nicotine replacement therapy (NRT) and non-nicotine EC.
• No detected difference in serious adverse events (SAEs) between EC and comparators, though evidence for safety remains low certainty.
• Living systematic review approach ensures continuous updating with emerging evidence.
• Main safety concerns include mild adverse events that often resolve with continued use.

Background