Intrathecal Morphine Significantly Enhances Postoperative Recovery Quality Following Laparoscopic Colorectal Surgery

MedXY Editorial Team•Dec 23, 2025•Anesthesiology

Intrathecal morphine (ITM) at a dose of 3 µg/kg, when combined with transversus abdominis plane block (TAPB), significantly improves the Quality of Recovery 15 (QoR-15) scores at 24 hours postoperatively.
The intervention group demonstrated a significant reduction in postoperative opioid consumption (morphine milligram equivalents) compared to the control group.
Despite the use of opioids, the ITM group experienced a lower incidence of postoperative nausea, though the incidence of pruritus was notably higher.
These findings suggest that ITM is a highly effective component of multimodal analgesia within an Enhanced Recovery After Surgery (ERAS) framework for laparoscopic colorectal procedures.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

Intrathecal morphine (ITM) at a dose of 3 µg/kg, when combined with transversus abdominis plane block (TAPB), significantly improves the Quality of Recovery 15 (QoR-15) scores at 24 hours postoperatively.
The intervention group demonstrated a significant reduction in postoperative opioid consumption (morphine milligram equivalents) compared to the control group.
Despite the use of opioids, the ITM group experienced a lower incidence of postoperative nausea, though the incidence of pruritus was notably higher.
These findings suggest that ITM is a highly effective component of multimodal analgesia within an Enhanced Recovery After Surgery (ERAS) framework for laparoscopic colorectal procedures.