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MedXY AI/MedXY News/Section: Neurology

Intervention Lowers Long‑Term Hemorrhage Risk in Unruptured Brain AVMs: Evidence From a Nationwide Target‑Trial Emulation

MedXY Editorial Team•Nov 19, 2025•Neurology
brain arteriovenous malformationtarget trial emulation

Highlights

Patients with unruptured brain arteriovenous malformations (AVMs) who underwent interventional treatment had higher 5‑year hemorrhage‑free survival (96.2%) than those managed conservatively (89.0%), with an absolute risk difference of 7.23% and hazard ratio 0.44.

Longer follow‑up (10 years) showed a sustained benefit (risk difference 8.37%; HR 0.56). Benefits were concentrated in low‑grade, compact nidus AVMs; no clear benefit was seen for high‑grade or diffuse nidus lesions.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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